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President Donald Trump says the US has carried out a "successful" bombing attack on three nuclear sites in Iran and said they have been "obliterated".
Israel says they were in "full co-ordination" with the US in planning the strikes.
Iranian officials have confirmed the facilities were struck but denied it had suffered a major blow.
One of the targets was Fordo a uranium enrichment plant hidden in a remote mountainside that is vital to Iran's nuclear ambitions.
The strikes mark a significant escalation in the ongoing war between Iran and Israel.